Viagra slows the visual response to flicker

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Viagra slows the visual response to flicker

As an undesirable side effect, sildenafil citrate (Viagra) partially inhibits the phosphodiesterase PDE6 [1], which plays an essential role in phototransduction (reviewed in [2,3]). PDE6 not only activates the visual transduction cascade, but also controls the time over which the visual response is integrated, thereby helping to maintain the size of the visual response within an optimal range a...

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Flickering lights can be uncomfortable to look at and can induce seizures in observers with photosensitive epilepsy. However, the temporal characteristics contributing to these effects are not fully known. In the spatial domain, one identified source of visual discomfort is when images have Fourier amplitude spectra that deviate from the natural (∼1/frequency, 1/f) statistical characteristics o...

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Reaction to Visual Flicker in the Newt Triturus

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Flicker distorts visual space constancy.

Effects of flicker on space perception were measured by displacing a flickering target during saccadic eye movements. A small target was flickered at 33, 66, 130 or 260 Hz. Using a 2-interval forced-choice design, sensitivity to the displacement was about twice as great when the target was moved in the direction opposite the eye movement as when it was moved in the same direction. This would be...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2006

ISSN: 0960-9822

DOI: 10.1016/j.cub.2006.01.016